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Cruises from Panama City to Miami

Are you looking for a cruise from Panama City to Miami? December, February and April are the most popular months to cruise between Panama City and Miami and there are 10 departures available from three of the world's leading cruise lines.
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10 Cruises (10 Cruise Departures)
12 Day Caribbean Quest Voyage with Azamara Cruises
Cruise
 (1)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 15 March 2026
Countries Visited: Panama, Colombia, Aruba, Bonaire (+3 more), Curacao, Dominican Republic, USA
INSIDE
$4,853
OCEANVIEW
$6,070
BALCONY
$7,179
SUITE
$9,030
From (per person) 4,853
View Trip
11 Day Captivating Panama Canal with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 April 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+3 more), Bonaire, Jamaica, USA
Bonus SavingsExclusive Deal
INSIDE
$4,314
OCEANVIEW
$4,778
BALCONY
$6,854
SUITE
$9,135
Save (per person) 2,506
From (per person) 4,314
View Trip
10 Day Panama Canal Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 13 December 2024
Countries Visited: Panama, Costa Rica, Honduras, Guatemala (+2 more), Mexico, USA
Circle Club Voyage
INSIDE
$1,923
OCEANVIEW
$2,012
BALCONY
$2,468
SUITE
-
From (per person) 1,923
View Trip
12 Day Classic Panama Canal with Oceania Cruises
Cruise
 (2)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 February 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+4 more), Bonaire, Jamaica, Bahamas, USA
Bonus SavingsExclusive Deal
INSIDE
$4,984
OCEANVIEW
$5,385
BALCONY
-
SUITE
$10,874
Save (per person) 2,586
From (per person) 4,984
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 04 April 2026
Countries Visited: Panama, Colombia, Curacao, Aruba (+3 more), Jamaica, Cayman Islands, USA
Exclusive Deal
INSIDE
$4,641
OCEANVIEW
$5,086
BALCONY
$7,462
SUITE
$10,293
Save (per person) 2,029
From (per person) 4,641
View Trip
11 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 10 November 2025
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
More At Sea OfferExclusive Solo Offer
INSIDE
$3,609
OCEANVIEW
$4,069
BALCONY
$5,291
SUITE
$5,675
From (per person) 3,609
View Trip
11 Day Canal & Coral Isles with Oceania Cruises
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 April 2026
Countries Visited: Panama, Colombia, Costa Rica, Honduras (+2 more), Mexico, USA
Exclusive Deal
INSIDE
$4,483
OCEANVIEW
$4,938
BALCONY
$7,314
SUITE
$10,145
Save (per person) 2,027
From (per person) 4,483
View Trip
10 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 11 December 2024
Countries Visited: Panama, Costa Rica, Jamaica, Cayman Islands (+3 more), Mexico, Bahamas, USA
More At Sea OfferExclusive Solo Offer
INSIDE
$1,752
OCEANVIEW
$1,782
BALCONY
$1,874
SUITE
$1,981
From (per person) 1,752
View Trip
12 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 16 February 2026
Countries Visited: Panama, Colombia, Aruba, Saint Lucia (+4 more), Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
More At Sea OfferExclusive Solo Offer
INSIDE
$3,788
OCEANVIEW
$4,324
BALCONY
$5,822
SUITE
$6,206
From (per person) 3,788
View Trip
12 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 09 February 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+4 more), Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
More At Sea Offer
INSIDE
$2,729
OCEANVIEW
$2,805
BALCONY
$5,299
SUITE
$5,374
From (per person) 2,729
View Trip
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